3-4c Carcinogenesis part 3
CARCINOGENESIS
I. BASIC PRINCIPLES
A. Cancer formation is initiated by damage to DNA of stem cells. The damage
overcomes DNA repair mechanisms, but is not lethal.
i. Carcinogens...
3-5 Tumor Progression
TUMOR PROGRESSIONI. TUMOR INVASION AND SPREAD
A. A ccu m u I at io n of mu t a t ion s eve nt ua...
3-6 Clinical Characteristics
NEOPLASIA
I. BASIC PRINCIPLES
A. Neoplasia is new I issue growth that is unregulated, irreversible, and monoclonal;
these features distinguish it from hyperplasia and repair.
B. Monoclonal means...